Anti-PDI Antibody

Protein Disulfide Isomerase (PDI), also called P4HB or ERp60, is a ~57 kDa thiol-disulfide oxidoreductase located in the endoplasmic reticulum, where it catalyzes the formation, isomerization, and reduction of disulfide bonds during nascent protein folding. This Rabbit polyclonal antibody from Antibodies.com targets PDI for use in Western blot, immunohistochemistry, and immunofluorescence workflows on human samples. Supplied as 100 µl of unconjugated antiserum, it supports studies of ER stress, the unfolded protein response, oxidative protein folding, and chaperone-assisted quality control in cell biology and pathology research. The reagent recognizes endogenous human PDI in fixed tissue sections, cell lysates, and cultured cells, making it a practical reagent for mapping UPR activation and ER-resident chaperone distribution across research models. The unconjugated format leaves the antibody compatible with secondary detection reagents chosen by the user, including HRP, biotin, or fluorophore conjugates, so the same vial can be deployed across colorimetric Western blot, chromogenic immunohistochemistry, and fluorescence imaging experiments.