Anti-PDHX Antibody

This polyclonal antibody targets PDHX (Pyruvate Dehydrogenase Complex Component X), the E3-binding protein subunit of the mitochondrial pyruvate dehydrogenase complex that catalyzes oxidative decarboxylation of pyruvate to acetyl-CoA. Raised in rabbit and supplied by Antibodies.com as an unconjugated polyclonal reagent in a 100 µL volume, the antibody is validated for Western blot and immunofluorescence workflows on human samples. PDHX tethers dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide acetyltransferase (E2) core, and investigators studying pyruvate dehydrogenase deficiency, neonatal lactic acidosis, Leigh syndrome, or broader mitochondrial metabolic regulation use this reagent to track expression and localization in cell and tissue models. The unconjugated format allows flexible pairing with secondary reporters of the researcher's choice for either immunoblotting membranes or fixed-cell imaging.