Anti-PDGFR-β Antibody

PDGFR-β (Platelet-Derived Growth Factor Receptor Beta) is a type III receptor tyrosine kinase that binds PDGF-BB and related ligands, driving mesenchymal proliferation, pericyte recruitment, and stromal remodeling during angiogenesis, wound healing, and fibrotic disease. This Antibodies.com polyclonal reagent, raised in rabbit and supplied as a 50 µl vial, is unconjugated and intended for research use only.

The antibody cross-reacts with the human, mouse, and rat orthologues, supporting comparative work across cell culture systems and in vivo tissue specimens. Validated applications include Western blot, immunohistochemistry, immunofluorescence, and ELISA, so a single lot can serve pathway studies, tissue mapping, and co-localization experiments.

Typical use cases include characterizing PDGFR-β expression in tumor stroma, profiling pericyte coverage in vascular networks, monitoring receptor phosphorylation downstream of PDGF stimulation, and screening kinase inhibitors. The unconjugated format allows pairing with HRP-, fluorophore-, or biotin-labeled secondary reagents depending on the detection platform. For long-term storage, keep the vial at -20 °C in working aliquots to limit freeze-thaw cycles and preserve antibody titer.