Anti-PDGFR α Antibody

PDGFRα (Platelet-Derived Growth Factor Receptor Alpha) is a 170 kDa receptor tyrosine kinase that transduces signals from PDGF-AA, PDGF-BB, and PDGF-CC ligands, governing mesenchymal cell proliferation, stromal recruitment, and tissue remodeling. This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against PDGFRα and validated for western blot, immunohistochemistry, and immunofluorescence across human, mouse, and rat specimens.

Anti-PDGFRα reagents support several active research areas: characterizing cancer-associated fibroblasts and pericytes within the tumor microenvironment, profiling interstitial mesenchymal populations in kidney, lung, and cardiac tissues, identifying fibroblast reticular cells in lymphoid organs, and assembling gastrointestinal stromal tumor panels. Additional applications include fibrosis and wound healing models, neural crest lineage tracing, and mesenchymal stem cell characterization.

Provided as 100 µl in a vial of unconjugated polyclonal antibody raised in rabbit host, the reagent is compatible with HRP, biotin, and fluorophore-conjugated secondary antibodies for chromogenic or fluorescence detection. Refrigerated short-term storage is recommended; aliquot and freeze at -20 °C for longer projects. For research use only.