Anti-PDGFR-β Antibody

Recombinant rabbit monoclonal primary antibody targeting the platelet-derived growth factor receptor beta (PDGFR-β), distributed by Antibodies.com as an unconjugated reagent. The clone was raised against the human receptor and is verified by the supplier for western blot and immunohistochemistry, making it a useful reagent for laboratories profiling perivascular, mesenchymal, and tumor-stromal compartments. Independent reviews of comparable recombinant rabbit anti-PDGFR-β clones note selective detection in FFPE tissue without cross-reactivity against the related PDGF receptor alpha family member, an important consideration when interpreting stromal versus epithelial staining patterns in tumor microenvironment studies.

The immunoglobulin is supplied as 100 µl of a buffered liquid formulation containing 1% BSA and 40% glycerol in TBS at pH 7.4, with 0.05% sodium azide added as a preservative. Because the conjugate is unconjugated, the reagent can be paired with an HRP- or fluorophore-tagged secondary antibody of the investigator's choice for chromogenic IHC, immunofluorescence, or standard immunoblotting. Investigators apply this reagent to characterize pericytes, vascular smooth muscle cells, fibroblasts, and cancer-associated fibroblasts in studies of angiogenesis, organ fibrosis, wound healing, and glioma or soft-tissue sarcoma biology, and reactivity has been confirmed across human, mouse, and rat samples.

For best results, store refrigerated at 2-8°C in the original vial and protect from light to preserve activity through multiple freeze-thaw cycles. The product is intended for research use only and is not validated for diagnostic or therapeutic applications. Detailed validation images and recommended dilution ranges are available on the Antibodies.com product page, where this primary antibody is catalogued alongside related markers for mesenchymal lineage tracing and vascular biology.