Anti-PDGF-D Antibody

Raised in rabbits against the human target and distributed by Antibodies.com, this polyclonal primary antibody recognizes platelet-derived growth factor D (PDGF-D), a secreted homodimeric mitogen that drives mesenchymal cell proliferation, pericyte recruitment, angiogenesis, and extracellular matrix remodeling. The reagent is supplied unconjugated in a 100 µl vial, allowing direct incorporation into established western blot and ELISA workflows without further purification or buffer exchange. Reactivity with human PDGF-D supports its use in cancer research models where PDGF-D signaling has been linked to tumor stromal interactions, in fibrotic disease studies of the kidney, lung, and liver, and in cardiovascular investigations of vascular injury and remodeling. The polyclonal format, generated in a rabbit host, presents a population of immunoglobulins directed against multiple epitopes on the PDGF-D polypeptide, which can improve detection of the protein under denaturing and reducing western blot conditions. The unconjugated format lets researchers pair the reagent with their preferred secondary antibody for chromogenic, chemiluminescent, or fluorescence-based readouts, and the absence of a covalently attached reporter maintains flexibility for downstream applications such as immunoprecipitation or antigen capture assays.