Anti-PDE4C Antibody

Raised in rabbit and supplied as an unconjugated, ready-to-use reagent in a 100 µl volume, this polyclonal antibody from Antibodies.com targets human Phosphodiesterase 4C (PDE4C) for laboratory research applications.

PDE4C is a cAMP-specific hydrolytic enzyme belonging to the PDE4 family (PDE4A, 4B, 4C, and 4D), where it regulates intracellular cyclic adenosine monophosphate levels and downstream signaling in inflammatory, neuronal, and airway tissues. Investigators studying second-messenger pathways, cAMP metabolism, or PDE4 inhibitor pharmacology use anti-PDE4C reagents to detect endogenous protein expression across human cell and tissue preparations.

Validated for Western blot (WB) and immunohistochemistry (IHC), the reagent supports detection of PDE4C in whole-cell lysates, tissue homogenates, and fixed paraffin-embedded sections. The unconjugated format allows flexible pairing with secondary reporters selected by the end user, including HRP, fluorophore, or biotin conjugates.

For long-term stability, the antibody is best stored at -20 °C in working aliquots; repeated freeze-thaw cycles should be avoided to preserve immunoglobulin activity. Aliquot upon receipt and protect from light when stored. For research use only; not intended for diagnostic or therapeutic procedures.