Anti-PDCD6 Antibody

A rabbit polyclonal IgG raised against human PDCD6, unconjugated and supplied by Antibodies.com in a 200 µl vial for western blot use. PDCD6 — also known as ALG-2 (apoptosis-linked gene 2) — is a penta-EF-hand calcium-binding adaptor that participates in programmed cell death signaling, endoplasmic reticulum stress responses, and ESCRT-associated membrane fission events.

The reagent detects endogenous PDCD6 in human cell lysates, producing a band close to the predicted ~21 kDa molecular weight on immunoblots. Common research contexts include apoptotic pathway analysis, calcium-dependent signaling studies, and mapping the ALG-2/ALIX interaction network relevant to cytokinesis and virus budding. Researchers should aliquot the vial upon arrival and store it frozen at -20 °C to limit freeze-thaw cycles; thaw on ice before each western blot session. For research use only.