Anti-PDCD6 Antibody

PDCD6, also called ALG-2 (apoptosis-linked gene 2), is a 22 kDa penta-EF-hand calcium-binding protein with central roles in programmed cell death, calcium-dependent membrane trafficking, and endosomal sorting. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against full-length human PDCD6 and validated for Western blot and immunofluorescence workflows, with cross-reactivity to mouse and rat orthologs. The antibody is supplied as 100 µl of polyclonal antiserum for standard immunodetection in cell lysates and fixed cell preparations. Researchers studying apoptosis pathways, ER-to-Golgi vesicle transport, and calcium-signalling biology use it to detect endogenous PDCD6 expression in human, mouse, and rat samples. The unconjugated format permits secondary antibody pairing for fluorescence or chemiluminescent detection systems. Storage at -20°C in working aliquots preserves activity across multiple freeze-thaw cycles limited to the IgG fraction.