Anti-PDCD10 Antibody

This polyclonal reagent from Antibodies.com targets programmed cell death protein 10 (PDCD10), also designated CCM3, a scaffold protein linked to cerebral cavernous malformation disease, stress-induced apoptosis, and VEGF-associated vascular signaling. Raised in rabbit and supplied as an unconjugated IgG, the antibody is validated for immunohistochemistry on formalin-fixed tissue sections and shows reactivity with both human and rat specimens, supporting comparative studies of neurovascular endothelium and brain tissue.

Each vial delivers 50 µl of reagent, ready to support IHC workflows. For handling, store at 4 °C for short-term use, and aliquot before freezing at -20 °C to protect against repeated freeze-thaw cycles. Because the antibody is unconjugated, laboratories can pair it with HRP, biotin, or fluorescent secondary reagents depending on the chosen detection chemistry and imaging platform.

Research applications include mapping PDCD10 expression in cavernous malformation lesions, probing apoptotic responses in cultured endothelial cells, and investigating the protein's interaction with MST kinases and the STRIPAK complex in cell signaling studies.