Anti-PCSK5 Antibody

PCSK5 (Proprotein Convertase Subtilisin/Kexin Type 5), also referred to as PC5 or PC6, is a calcium-dependent serine protease of the subtilisin/kexin family that cleaves a broad spectrum of pro-protein substrates at paired basic residues during transit through the secretory pathway and at the cell surface. This unconjugated rabbit polyclonal reagent from Antibodies.com, supplied as a 100 µl aliquot, was raised against recombinant PCSK5 and is validated for Western blot detection of endogenous PCSK5 in human, mouse, and rat samples. The polyclonal IgG format provides recognition of multiple epitopes across the full-length convertase, which is useful when probing both precursor and processed forms in tissues such as brain, kidney, and heart where PCSK5 has documented developmental and metabolic roles. For best results, aliquot the reagent on receipt and store at -20 °C, avoiding repeated freeze-thaw cycles; the product is intended for research use only and is not validated for diagnostic or clinical applications.