Anti-PCNA Antibody

Raised in rabbit against the Proliferating Cell Nuclear Antigen, this unconjugated polyclonal antibody from Antibodies.com detects a nuclear protein that functions as the processivity factor for DNA polymerase delta during DNA replication and repair. The reagent is supplied as a 50 µl aliquot and is validated for western blot, immunohistochemistry, immunofluorescence, and immunoprecipitation workflows across Human, Mouse, and Rat samples.

Designated Anti-PCNA Antibody, the reagent serves as a common proliferation marker in tumor biology, stem cell characterization, and tissue regeneration studies. Researchers apply it to score dividing cells in paraffin-embedded sections, monitor replication factor loading in chromatin fractions, and profile DNA damage response signaling alongside markers such as Ki-67 and cyclin D1. The polyclonal format recognizes multiple epitopes on the PCNA homotrimer, which is useful when working with fixed tissue or denatured lysates where conformational epitopes may be lost.

Store the vial refrigerated and protected from light; aliquot upon arrival to limit freeze-thaw cycles and preserve antibody activity across the shelf life. For research use only.