Anti-PCMT1 Antibody

PCMT1 (Protein-L-isoaspartate (D-aspartate) O-methyltransferase) is a SAM-dependent methyltransferase that catalyzes repair of age-damaged proteins by converting abnormal L-isoaspartyl residues back to normal L-aspartyl residues. This Rabbit polyclonal antibody from Antibodies.com is raised against PCMT1 and validated for Western blot, immunohistochemistry, and immunofluorescence workflows across Human, Mouse, and Rat samples.

The reagent is supplied unconjugated at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, packaged in a 100 µl vial ready for direct dilution into assay buffer. The polyclonal format enables recognition of multiple epitopes on the target, supporting reproducible detection in cell lysate and tissue-section applications, including studies of proteostasis and cellular aging.

Store at -20°C in aliquots to limit freeze-thaw cycles and preserve activity. For Western blot, expect a band consistent with the ~25 kDa PCMT1 protein; for IHC and IF, optimize antigen retrieval and blocking conditions for each sample type. Intended for research use only.