Anti-PCM1 Antibody

PCM1 (Pericentriolar Material 1) is a large centrosomal scaffold protein that organizes centriolar satellites and supports primary cilium assembly, mitotic spindle integrity, and the DNA damage response. This unconjugated rabbit polyclonal reagent from Antibodies.com targets PCM1 for western blot and immunohistochemistry workflows, with reactivity confirmed across human, mouse, and rat samples. Supplied as 100 µl volumes, the antibody enables immunolabeling studies of centrosome architecture and ciliogenesis in fixed cells and tissue sections. Researchers investigating Bardet-Biedl syndrome, thyroid papillary carcinoma-associated PCM1-RET translocations, and mitotic checkpoint regulation use this reagent to track satellite dispersal, centrosome duplication cycles, and BBS protein complex recruitment. The unconjugated format permits flexible pairing with custom fluorophore or enzyme conjugates for both fluorescence and chromogenic detection in cell-based and histological preparations.