Anti-PCBP2 Antibody

This rabbit polyclonal reagent from Antibodies.com targets PCBP2, a multifunctional RNA-binding protein belonging to the poly(C)-binding family. PCBP2 binds poly(C) tracts in mRNA and participates in mRNA stabilization, translational control, and iron homeostasis through recognition of iron-responsive elements (IREs) in transcripts such as ferritin and the transferrin receptor. The antibody has been validated for Western blot (WB), immunohistochemistry (IHC), and immunofluorescence (IF) applications and cross-reacts with human, mouse, and rat samples, supporting use across comparative cell biology and animal model studies. Supplied as 100 µl of unconjugated antisera, the reagent is intended for research use only and is commonly cited in investigations of viral replication (including poliovirus IRES-driven translation), hypoxic stress responses, and post-transcriptional gene regulation in cancer cell lines.