Anti-PBX2 Antibody

PBX2 (pre-B-cell leukemia homeobox 2) is a ubiquitously expressed TALE/PBX homeobox transcription factor that maps to chromosome 6p21.32 within the major histocompatibility complex and acts as a transcriptional activator at the TLX1 promoter, where it cooperates with MEIS1 and HOXA9 in heterodimeric and heterotrimeric complexes. This rabbit polyclonal IgG reagent from Antibodies.com is supplied as a 200 µl unconjugated liquid aliquot, allowing laboratories to pair it with a labeled secondary antibody of their choice for western blot detection of endogenous PBX2 in mouse and rat samples. The antibody is validated for western blot applications and suits workflows that compare PBX2 abundance across treated versus control lysates, validate experimental perturbations, or interrogate differentiation and signaling pathways in hematopoietic and other cellular models. Researchers should optimize working dilution empirically, include appropriate positive and negative controls, and consult the supplied lot-specific documentation for handling instructions, recommended storage temperature, and shelf-life information.