Anti-PBR Antibody

For neuroinflammation and mitochondrial research, this recombinant rabbit monoclonal antibody from Antibodies.com recognizes PBR (Peripheral Benzodiazepine Receptor), an 18 kDa outer mitochondrial membrane protein now commonly referenced as TSPO (Translocator Protein). PBR participates in cholesterol translocation into mitochondria — a rate-limiting step in steroid hormone biosynthesis — and is broadly used as a marker of microglial activation in studies of neurodegeneration. The antibody is provided as a 100 µl liquid formulation in TBS buffer (pH 7.4) containing 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative; aliquot upon receipt to limit freeze-thaw cycles, and store at -20 °C for long-term stability.

Validated for Western blot, immunocytochemistry and immunofluorescence on fixed cells, immunohistochemistry on tissue sections, immunoprecipitation, and flow cytometry, this unconjugated reagent detects the target in both human and mouse samples. Common research applications include mapping microglial reactivity in CNS tissue, profiling steroidogenic cells in adrenal and gonadal tissue, and investigating mitochondrial outer membrane protein composition in disease models.