Anti-PAX3 Antibody

Raised in rabbit as a polyclonal reagent against the PAX3 transcription factor, this unconjugated primary antibody from Antibodies.com supports protein detection across western blot, immunohistochemistry, and immunofluorescence workflows. The 100 µl aliquot is supplied in a vial and is validated for reactivity with human, mouse, and rat samples, making it useful for cross-species studies in developmental biology and oncology. PAX3 is a paired-box homeodomain factor essential for neural crest cell specification, melanocyte lineage commitment, and skeletal myogenesis, and aberrant PAX3 activity, including the PAX3-FOXO1 fusion characteristic of alveolar rhabdomyosarcoma, makes it a frequent target in cancer research and tumor diagnostics. For handling, store the antibody frozen at -20 °C in working aliquots to limit freeze-thaw cycles and protect from light; allow it to equilibrate before use in immunostaining or blot preparations. Researchers working on Waardenburg syndrome models, neural crest derivatives, or melanoma marker panels will find this reagent a flexible tool for both tissue-section and lysate-based assays.