Anti-PARP8 Antibody

This Rabbit polyclonal reagent from Antibodies.com targets PARP8, a member of the poly(ADP-ribose) polymerase enzyme family. The unconjugated antibody is supplied as 100 µl of liquid in a single-use vial, validated for western blot and immunohistochemistry workflows on Human and Mouse sample types.

PARP8, also called ARTD17, functions as a mono-ADP-ribosyltransferase that modifies substrate proteins post-translationally. Published studies have linked PARP8 activity to stress granule assembly, regulation of innate immune signaling, and antiviral defense pathways, including suppression of hepatitis B virus replication in hepatocytes. The polyclonal format allows recognition of multiple epitopes across the full-length protein, useful for probing variable expression levels and detecting truncated isoforms in cell lysates and fixed tissue sections. For best results, aliquot upon arrival, refrigerate the antibody vial, and limit freeze-thaw cycles to preserve binding activity.