Anti-PAPSS1 Antibody

This Rabbit polyclonal antibody from Antibodies.com targets PAPSS1 (3'-phosphoadenosine-5'-phosphosulfate synthase 1), the bifunctional enzyme that synthesises PAPS, the universal sulfuryl donor consumed by cellular sulfotransferases. Supplied as a 100 µl aliquot of unconjugated IgG raised in Rabbit, the reagent is validated for western blot detection of the human PAPSS1 protein, which carries both ATP-sulfurylase and APS kinase activities and supports sulfation pathways including heparan sulfate biosynthesis and the modification of hormones, neurotransmitters, and xenobiotics. The polyclonal, unconjugated format enables downstream labelling in custom assays and research into cartilage and bone development, spondyloepimetaphyseal phenotypes linked to the PAPSS2 paralog, and general sulfation metabolism. Aliquot and store frozen at -20 °C, protect from light, and limit freeze-thaw cycles to preserve reagent activity. This primary antibody is intended for research use only and reacts with the human PAPSS1 target.