Anti-PANX1 Antibody

Pannexin 1 (PANX1) is a single-membrane channel-forming glycoprotein that mediates ATP release and purinergic signaling at the plasma membrane, and this polyclonal reagent from Antibodies.com is raised in rabbit against the human PANX1 protein for detection across multiple immunoassay workflows. The antibody is supplied as 100 µl of a 1 mg/ml solution in PBS with 0.1% sodium azide and 50% glycerol as cryoprotectant, which keeps the antibody liquid for short-term handling at 4 °C and longer-term storage at -20 °C. Validated applications include Western blot, immunohistochemistry, and immunofluorescence on human samples, providing flexibility for studying PANX1 distribution in cell lines and fixed tissue sections. Because the reagent is unconjugated, it can be paired with a secondary detection system chosen by the researcher, and the polyclonal host background supports robust signal amplification in tissues where endogenous PANX1 expression is modest. Investigators working on inflammasome activation, apoptotic or eryptotic ATP release, and gap-junction-independent intercellular communication routinely use PANX1 antibodies to localize channel expression in neural, epithelial, vascular, and immune cell preparations.