Anti-PALLD Antibody

Raised in rabbit against the cytoskeletal scaffold protein palladin, this unconjugated polyclonal reagent from Antibodies.com is calibrated for Western blot detection across human, mouse, and rat samples. Palladin (PALLD) nucleates and cross-links actin bundles at focal adhesions, integrating mechanical cues into cell motility, migration, and extracellular matrix remodeling, and its deregulated expression is reported in invasive pancreatic ductal adenocarcinoma, breast carcinoma, and stromal fibroblasts remodeling the tumor microenvironment. The antibody is supplied at 1 mg/ml in phosphate buffered saline with 15 mM sodium azide at approximately pH 7.2, packaged as a 100 µl vial for routine immunoblotting of whole-cell lysates. Researchers probing actin cytoskeleton dynamics, focal adhesion biology, or tumor-stroma cross-talk can deploy the reagent as a primary incubation layer at working dilutions tuned to their substrate and detection chemistry. The unconjugated format allows pairing with HRP- or fluorophore-conjugated secondary antibodies of the researcher's choice, supporting chemiluminescent or fluorescent readouts. Brief handling notes: protect the vial from light, keep refrigerated, and avoid repeated freeze-thaw cycles; aliquot on first use to preserve the sodium azide-stabilized formulation.