Anti-PAK5 (E693) Antibody

Engineered for high-specificity detection of the p21-activated kinase 5 (PAK5) target, this affinity reagent from Antibodies.com is a rabbit polyclonal antibody raised against the E693 epitope region of human PAK5. It is supplied as a 50 µl liquid formulation at 1 mg/ml in phosphate buffered saline (PBS), pH approximately 7.2, containing 0.05% sodium azide as a preservative, and is unconjugated, allowing flexible downstream labeling. The host species is rabbit, the clonality is polyclonal, and the immunoglobulin class is IgG. Validation has been performed for Western blot (WB) and immunohistochemistry (IHC) workflows, and the reagent has been confirmed to cross-react with human, mouse and rat samples, making it suitable for a wide range of neuroscience and cell signalling studies. PAK5 is a member of the PAK family of serine/threonine kinases that carries an N-terminal CDC42/Rac interactive binding (CRIB) motif and a C-terminal Ste20-like kinase domain, and it is preferentially expressed in mammalian brain. For optimal stability, the antibody should be stored short term at 4 °C, with longer term storage by aliquoting at -20 °C and avoiding repeated freeze–thaw cycles. Researchers using this Antibodies.com reagent can expect reliable detection of endogenous PAK5 in lysates and tissue sections across the indicated species, supporting studies of kinase signalling, cytoskeletal regulation and neuronal development.