Anti-PAK1 (phospho T423) + PAK2 (phospho T402) + PAK3 (phospho T421) Antibody - Identical to Novus (NB100-82131)

From Antibodies.com, this polyclonal phospho-specific reagent recognizes the activated forms of the p21-activated kinase family at their conserved activation loop threonine residues (PAK1 T423, PAK2 T402, PAK3 T421). These phosphorylation events mark catalytically active kinase and are commonly studied in the context of growth factor signaling, cytoskeletal remodeling, and neuronal development pathways. The rabbit IgG antibody is supplied unconjugated in a 50 µL vial, allowing flexible selection of compatible secondary reagents for chromogenic immunohistochemistry or fluorescence imaging workflows. Validated reactivity spans human, mouse, and rat samples, supporting translational studies across cell lines, primary cultures, and tissue specimens. The polyclonal format provides recognition of multiple epitopes within the conserved phospho-threonine motif, increasing robustness when investigating kinase activation dynamics. Researchers commonly apply this reagent to formalin-fixed paraffin-embedded sections and frozen tissue preparations to localize sites of active PAK signaling in tumor, brain, and other model tissues. Aliquot upon receipt and avoid repeated freeze-thaw cycles to maintain phospho-epitope binding affinity. Intended for research use only in cell culture and tissue-based assays.