Anti-PAK1 (Ab-212) Antibody

This polyclonal reagent from Antibodies.com recognizes an epitope located near amino acid 212 of human PAK1 (p21-activated kinase 1), a serine/threonine kinase involved in cytoskeletal remodelling, focal adhesion turnover, MAPK cascade activity, and growth-factor-driven cell migration. The antibody was raised in rabbit and is supplied unconjugated, giving researchers flexibility to pair it with their preferred HRP, biotin, or fluorophore-conjugated secondaries.

Provided as 100 µl of antiserum for western blot, immunofluorescence, and immunohistochemistry workflows on human, mouse, and rat samples. The polyclonal format tolerates minor sequence variation between species, supporting comparative signalling studies and orthologous-tissue screens where PAK1 phosphorylation and expression are being tracked across model systems.

The PAK1 target is widely investigated in cancer cell motility, neuronal development, and immune signalling research, making it a useful marker for pathway-focused work on Rac1/Cdc42-driven cytoskeletal responses. Aliquot upon first thaw to limit freeze-thaw cycles and protect from light when working with fluorescent secondaries. Long-term storage at -20 °C in working aliquots preserves antibody activity across multiple experiments.