Anti-PAK1 / 2 (Ab-199) Antibody

This polyclonal antibody from Antibodies.com targets the p21-activated kinase 1/2 (PAK1/2) region surrounding the Ab-199 epitope, a site implicated in kinase activation and autophosphorylation. Raised in rabbit and supplied as 100 µL of unconjugated sera, the reagent is validated for Western blot (WB) and immunohistochemistry (IHC) workflows across human, mouse, and rat sample types.

The antibody recognizes endogenous levels of PAK1 and PAK2 proteins, supporting studies of cytoskeletal remodeling, MAPK signaling cascades, and downstream effector phosphorylation in growth and migration research. As a polyclonal reagent, it offers broader epitope coverage than monoclonal alternatives, which can help when probing conserved kinase domains.

For handling, the vial should be refrigerated in single-use aliquots to preserve antibody activity and minimize repeated freeze-thaw cycles. Working dilutions should be titrated empirically against the target cell or tissue lysate.