Anti-PAICS Antibody

The Antibodies.com catalog entry for this primary antibody targets PAICS (phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole succinocarboxamide synthetase), a bifunctional enzyme that catalyzes the sixth and seventh steps of the de novo purine biosynthesis pathway. Raised in rabbit and purified as an unconjugated polyclonal reagent, the antibody is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, and is packaged as a 100 µl aliquot suitable for repeated western blot and immunohistochemistry experiments on human, mouse, and rat specimens. PAICS has attracted growing attention in oncology research because elevated expression supports nucleotide supply in rapidly dividing cells, and a validated polyclonal reagent such as this one is useful for profiling enzyme levels, mapping tissue distribution by IHC, and tracking pathway activity in cell-based studies. For research use only.