Anti-PAFAH2 Antibody

The PAFAH2 target (Platelet-Activating Factor Acetylhydrolase 2) is a group VII phospholipase A2 that inactivates platelet-activating factor by cleaving its sn-2 acetyl group, and also hydrolyzes oxidatively fragmented phospholipids generated during oxidative membrane damage. This unconjugated rabbit polyclonal primary antibody from Antibodies.com is supplied as 100 µl of liquid reagent and recognizes the ~44 kDa human protein.

Validated applications include Western blot on human cell lysates and immunohistochemistry on fixed tissues. For best results, briefly centrifuge the vial before opening, aliquot to limit freeze-thaw cycles, and store at -20 °C; thawed aliquots may be kept refrigerated for short-term use.

PAFAH2 is expressed in many human tissues, with prominent levels in liver and kidney, where it contributes to phospholipid turnover and protection against oxidative lipid injury. The polyclonal format recognizes multiple epitopes on the target, supporting detection in denatured lysate samples and of native distribution in fixed sections.