Anti-PACSIN2 Antibody

A response-ready rabbit polyclonal IgG reagent against PACSIN2 (Protein Kinase C and Casein Kinase Substrate In Neurons 2), a membrane-curvature protein that links dynamin-mediated endocytosis to the actin cytoskeleton and is implicated in caveolar trafficking, vesicle scission, and receptor internalization.

Manufactured by Antibodies.com, this unconjugated primary antibody is raised in rabbit and supplied as 100 µl of liquid antiserum, suitable for Western blot, immunohistochemistry, and immunofluorescence applications on human and mouse samples. The polyclonal format allows recognition of multiple epitopes across the PACSIN2 target, which can be advantageous for detecting denatured protein in immunoblots or probing fixed tissue sections in immunohistochemistry workflows.

Because the reagent is unconjugated, laboratories can match it to HRP, biotin, or fluorophore-labeled secondary antibodies depending on the experimental read-out. Endogenous PACSIN2 has been studied in the context of caveolae-mediated endocytosis, insulin granule trafficking, and intracellular vesicle formation, making this reagent broadly applicable to cell biology research in membrane dynamics and cytoskeletal remodeling.