Anti-PACSIN1 Antibody

This polyclonal antibody from Antibodies.com targets PACSIN1 (Protein Kinase C and Casein Kinase Substrate In Neurons 1), a neuron-enriched membrane-associated protein best known for its role in synaptic vesicle endocytosis and vesicle trafficking. PACSIN1 binds dynamin, and its F-BAR domain shapes and tubulates membranes while SH3-domain interactions recruit the actin-nucleating machinery through N-WASP, linking membrane curvature to cytoskeletal remodeling at nerve terminals. The unconjugated rabbit IgG reagent is supplied as 200 µl of liquid and is validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples, making it a useful tool for neuroscience and cell biology laboratories studying synaptic function, neuronal development, or vesicle dynamics. Each vial should be aliquoted to limit freeze-thaw cycles, stored refrigerated for short-term use, and kept frozen at lower temperatures for long-term stability.