Anti-PABPC3 Antibody

This unconjugated polyclonal antibody from Antibodies.com specifically targets PABPC3, a cytoplasmic poly(A)-binding protein that participates in mRNA translation, stability control, and deadenylation in eukaryotic cells. The reagent is raised in rabbit and supplied as 100 µl of ready-to-use antibody, intended for researchers working with human samples in Western blot and immunohistochemistry workflows. As a member of the poly(A)-binding protein family, PABPC3 contributes to post-transcriptional gene regulation by binding the 3' poly(A) tail of messenger RNA, supporting translation initiation complex assembly and influencing mRNA turnover. The antibody is validated for reactivity with human PABPC3 and is unconjugated, allowing investigators to pair it with their preferred secondary detection reagents. Suitable applications include Western blot analysis of cell and tissue lysates to detect endogenous PABPC3 expression, as well as immunohistochemistry on fixed sections for studying protein localization. Researchers investigating germ cell biology, spermatogenesis, or post-transcriptional regulatory mechanisms will find this reagent useful for characterizing PABPC3 distribution and expression patterns in relevant tissues.