Anti-p90RSK (Ab-352) Antibody

This polyclonal antibody from Antibodies.com recognizes p90RSK (also called RSK1 or RPS6KA1), a serine/threonine kinase that operates downstream of ERK1/2 in the MAPK signaling cascade. The Ab-352 designation indicates the antibody was raised against a peptide epitope in the region surrounding residue 352 of the human protein, providing a reagent for monitoring kinase expression across cell and tissue samples.

Validated for western blot (WB) and immunohistochemistry (IHC), the antibody shows reactivity with human, mouse, and rat samples, enabling comparative studies across model systems. The unconjugated format gives flexibility in choosing secondary antibodies and detection chemistries, and the polyclonal composition allows recognition of multiple epitopes on the target kinase.

Each vial contains 100 ul of antibody. Store at -20 °C in working aliquots to limit freeze-thaw cycles. Researchers studying MAPK signaling, CREB phosphorylation, cell proliferation, and growth factor responses can use this reagent to map RSK-dependent pathways in their experimental systems.