Anti-p73 Antibody

This unconjugated rabbit polyclonal antibody from Antibodies.com is raised against human p73, a transcription factor of the p53 tumor-suppressor family that regulates apoptosis, DNA damage responses, and developmental cell fate decisions through multiple N-terminal isoforms, including the full-length TAp73 and the dominant-negative ΔNp73 variants.

The reagent is supplied at 100 µl volume and is validated for western blot and immunohistochemistry on human samples. Its unconjugated format allows pairing with user-selected secondary antibodies and chromogenic or fluorescent detection chemistries, supporting studies of isoform-specific expression in tissue microarrays, formalin-fixed paraffin-embedded sections, and cultured cell lysates.

p73 biology is relevant to neurogenesis, ciliogenesis, chemosensitivity, and several cancer contexts, and antibodies such as this are routinely used to profile TP73 status alongside related p53-family targets in tumor and normal tissue panels. Refer to the enclosed product datasheet for recommended storage conditions, working dilution ranges, and antigen-retrieval parameters appropriate for IHC applications.