Anti-p70 S6 kinase α Antibody

Supplied as 100 µl of unconjugated rabbit polyclonal antiserum from Antibodies.com, this reagent specifically targets p70 S6 kinase α, a 70 kDa serine/threonine kinase that operates downstream of mTORC1. The kinase phosphorylates ribosomal protein S6 to drive translational control of mRNAs encoding ribosomal proteins and translation factors, and it is widely studied in connection with cell growth, proliferation, autophagy, and metabolic regulation. Validated for western blot, immunohistochemistry, and ELISA workflows, the antibody binds the human, mouse, and rat orthologues of the target, making it useful across common model systems. Polyclonal reactivity offers recognition of multiple epitopes on p70 S6 kinase α, which is helpful for detecting both the full-length p85 precursor and the shorter p70 mature form. The unconjugated format allows researchers to choose their own secondary reporter and detection chemistry, from HRP and fluorophore conjugates to biotin-streptavidin systems. Aliquot upon arrival, store refrigerated, and avoid repeated freeze-thaw cycles to preserve titre. Intended for research use only.