Anti-p70 S6 kinase α Antibody

This rabbit polyclonal antibody targets p70 S6 kinase α, a serine/threonine kinase positioned downstream of mTOR complex 1 that phosphorylates ribosomal protein S6 to control translation, cell growth, and metabolic homeostasis. Researchers working in cancer biology, metabolism, and neuroscience deploy the reagent from Antibodies.com to interrogate PI3K/AKT/mTOR pathway activity in primary tissues and cultured cell lines, where its unconjugated format allows flexible pairing with secondary detection chemistries. Validated applications cover western blot analysis of phosphorylated signaling intermediates, immunohistochemistry on fixed tissue sections, immunofluorescence imaging of subcellular kinase distribution, and ELISA quantification, with reactivity confirmed against human, mouse, and rat samples so a single lot supports cross-species comparative studies. Each vial contains 50 µl of polyclonal serum, sufficient for multiple immunoblot experiments when diluted according to standard protocols. Store refrigerated at 4 °C for short-term use, or aliquot and freeze at -20 °C to preserve activity across repeated freeze-thaw cycles, and handle gently to avoid bubble-induced denaturation. This product is intended for research use only and fits naturally into workflows studying translation regulation, insulin signaling, autophagy, and pathway responses to nutrient, growth factor, or pharmacological stimuli.