Anti-p53 (G372) Antibody

This rabbit polyclonal reagent targets the C-terminal region of human p53 at the G372 epitope, a region frequently used in tumor pathology workups to detect stabilized or mutant protein. Supplied by Antibodies.com as a 50 µL aliquot at 1 mg/mL in phosphate buffered saline (pH 7.2) with 0.05% sodium azide as preservative, the unconjugated antibody is validated for immunohistochemistry on formalin-fixed paraffin-embedded tissue and cross-reacts with mouse and rat samples in addition to human specimens. Researchers apply it to study TP53 status in cancer biopsies, apoptosis pathways, and DNA damage response models where elevated nuclear staining serves as a surrogate marker for underlying TP53 alterations.