Anti-p53 Antibody

Raised in rabbits against the p53 tumor suppressor (encoded by the TP53 gene), this polyclonal unconjugated primary antibody from Antibodies.com is supplied as a 50 µl vial for research use. The reagent detects p53 in human and monkey samples and is validated for western blot, where it reveals the characteristic band near 53 kDa, as well as for ELISA-based assays. Because p53 governs cell cycle arrest, the DNA damage response, and programmed cell death (apoptosis), this antibody is a staple of cancer biology research and genotoxicity screening. Polyclonal recognition across multiple epitopes helps capture different p53 isoforms and many naturally occurring mutant variants of TP53 found in tumor samples. The unconjugated format gives laboratories the freedom to conjugate the antibody to HRP, Alexa Fluor dyes, biotin, or other labels chosen for a specific experimental setup. For best results, keep the vial refrigerated, aliquot to minimize freeze-thaw cycles, and protect from light to preserve antibody activity.