Anti-p53 Antibody

Raised in rabbit, this unconjugated polyclonal antibody recognizes the p53 tumor suppressor and is validated for western blot, immunohistochemistry, and ELISA workflows. The reagent ships as 50 µl of liquid in a single-use vial, ready to dilute into established lab protocols without further preparation.

Reactivity has been confirmed against human, mouse, and rat samples, supporting studies in cell culture, xenograft tissue, and patient-derived specimens where p53 status is being characterized. Researchers use this reagent to monitor p53 stabilization following genotoxic stress, to map mutation-driven accumulation in tumor sections, and to probe the DNA damage response and apoptosis pathways that p53 regulates.

The polyclonal format allows recognition of multiple epitopes across the full-length protein, which is useful when working with truncated splice variants or post-translationally modified forms of the target.

From Antibodies.com, the antibody is intended for research use only and is shipped refrigerated for short-term stability.