Anti-p53 Antibody

Generated against the p53 tumor suppressor, this rabbit polyclonal reagent from Antibodies.com recognizes multiple epitopes of the TP53-encoded protein, supporting both qualitative and semi-quantitative detection across diverse sample types.

Mutations in TP53 occur in the majority of human cancers, making robust p53 detection essential for oncology research, DNA damage response studies, and apoptosis pathway investigations. The unconjugated antibody is validated for Western blot, immunohistochemistry, immunofluorescence, and ELISA workflows, with confirmed reactivity against human, rat, and monkey samples.

Researchers apply it to monitor p53 expression and subcellular localization in tumor cell lines, xenograft tissue sections, and primary biopsy specimens. Each vial contains 50 µL of antibody, supplied unconjugated for flexible pairing with secondary detection reagents or custom labeling in specialized assay development.