Anti-p53 (Acetyl-K370) Antibody

Recognizing the acetylated form of the p53 tumor suppressor at lysine 370, this recombinant rabbit monoclonal antibody from Antibodies.com targets a post-translational mark that enhances sequence-specific DNA binding and transcriptional activation of downstream effectors such as p21 during the DNA damage response. Supplied as 50 µl of unconjugated reagent in 1×TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative, it is validated for Western blot (WB) and immunocytochemistry/immunofluorescence (ICC/IF) applications on human, mouse, and rat samples. The recombinant monoclonal format supports reproducible detection of K370-acetylated p53 in studies of apoptosis, genotoxic stress signaling, and tumor suppressor pathway analysis, where discriminating the activated, acetylated pool from total p53 levels is essential for interpreting p53-dependent transcriptional outcomes.