Anti-P4HTM Antibody

P4HTM is a transmembrane prolyl 4-hydroxylase domain enzyme best known for its role in cellular oxygen sensing and regulation of hypoxia-inducible factor (HIF) signalling. This rabbit polyclonal IgG reagent from Antibodies.com is raised against the human and mouse P4HTM target, supplied unconjugated in a 50 µL vial and validated on these two species. The antibody is intended for research use in western blot workflows, where it can be applied to lysates from cell lines or tissue samples to characterise P4HTM protein expression under normoxic versus hypoxic conditions. Because P4HTM contributes to HIF-1α hydroxylation and turnover, the reagent is frequently used by researchers studying hypoxia signalling, ischemic response, and prolyl hydroxylase domain (PHD) biology in cardiovascular, cancer, and metabolic models. Storage handling recommendations include aliquoting upon receipt to limit freeze-thaw cycles, with working stocks held refrigerated for short-term use; the format is a single-use liquid antibody preparation.