Anti-P4HB Antibody

Protein disulfide isomerase, the product of the P4HB gene, is an endoplasmic reticulum-resident enzyme that catalyzes the formation, breakage, and rearrangement of disulfide bonds during nascent protein folding, and also serves as a chaperone for misfolded substrates. This unconjugated rabbit polyclonal reagent from Antibodies.com is raised against P4HB and binds the endogenous target in human, mouse, and rat samples, enabling detection across the species most often used in cell biology and disease-model studies.

The reagent is supplied at 1 mg/ml in a PBS buffer containing 0.1% sodium azide and 50% glycerol, packaged as a 100 µl vial that supports multiple experimental runs. Store refrigerated after receipt and protect from light to preserve activity; aliquot on first use to limit repeated freeze-thaw cycles. Recommended applications include Western blot, immunohistochemistry on fixed tissue sections, immunofluorescence imaging, immunoprecipitation of native complexes from lysates, and RNA immunoprecipitation workflows that probe P4HB-associated transcripts.