Anti-p38 (phospho-Y182) Antibody

Phosphorylation at Y182 within the p38 MAPK activation loop is the target of this rabbit polyclonal reagent from Antibodies.com, raised against the dually phosphorylated motif that drives full kinase activity. By recognizing the phospho-Y182 form specifically, the antibody lets researchers distinguish activation-state signaling from baseline p38 expression in stress, inflammatory, and differentiation pathways.

Validated for Western blot (WB) and immunohistochemistry (IHC) on Human, Mouse, and Rat samples, the reagent supports both cell-line signaling studies and tissue-based pathology work. Each vial is supplied at 1 mg/ml in phosphate buffered saline (PBS) with 15 mM sodium azide at approximately pH 7.2, and the 100 µl pack size covers multiple immunoblots or staining runs. The unconjugated format allows flexible pairing with HRP-, biotin-, or fluorophore-labeled secondaries for chemiluminescent or chromogenic detection workflows.