Anti-p300 Antibody

This rabbit polyclonal antibody from Antibodies.com targets the p300 transcriptional coactivator, a histone acetyltransferase involved in chromatin remodeling, cell cycle progression, and tumor suppressor signaling. Raised in rabbits and supplied as an unconjugated reagent in a 100 µl vial, the reagent is validated for Western blot, immunohistochemistry, and ELISA workflows on human samples. Investigators commonly apply it to study EP300-dependent histone acetylation, transcription factor coactivation, and chromatin modification pathways relevant to cancer biology and Rubinstein-Taybi syndrome research. The polyclonal format increases the likelihood of recognizing multiple epitopes across the full-length p300 protein, supporting detection in cell lysates and fixed tissue sections. Store refrigerated at 2 to 8 degrees C and avoid repeated freeze-thaw cycles to preserve binding activity. Intended for research use only.