Anti-P2X3 Antibody

Generated in rabbit, this polyclonal reagent from Antibodies.com targets the P2X3 subunit of ATP-gated cation channels, which are concentrated on small-diameter sensory neurons in dorsal root and trigeminal ganglia. Researchers studying nociception, neuropathic pain pathways, and visceral hypersensitivity use it to detect endogenous receptor protein in human, mouse, and rat samples by Western blot and ELISA. The unconjugated preparation is supplied as 100 µl of antiserum, suited for immunoblotting membrane-bound channels and probing tissue lysates under reducing conditions. P2X3 has attracted interest as a translational target in chronic cough and bladder overactivity research, where antibody-based detection helps map receptor expression in relevant afferent fibers.