Anti-P2RY6 Antibody

The P2Y6 receptor (encoded by P2RY6) is a G-protein coupled receptor that binds UDP and signals through Gq/11 to activate phospholipase Cβ pathways in epithelial, immune, and neuronal cell populations. This Rabbit polyclonal antibody from Antibodies.com is raised against the human P2RY6 receptor and is validated for Western blot and immunohistochemistry applications on human samples. Supplied as 100 µl of unconjugated antisera in a single vial, it gives labs flexibility to pair it with their own secondary detection reagents and label of choice. Researchers commonly use anti-P2RY6 antibodies to map receptor distribution across epithelial barriers, profile UDP-driven microglial responses in neuroinflammation models, and characterize phagocytic signaling in macrophage populations. The polyclonal format recognizes multiple epitopes on the target, which can strengthen signal in tissues where P2Y6 is expressed at low levels or where post-translational modifications might shield any single epitope. Store refrigerated; aliquot upon first thaw to limit freeze-thaw cycles and preserve antibody activity across extended studies.