Anti-P2RY2 Antibody

This polyclonal reagent from Antibodies.com targets the human and mouse P2RY2 purinergic G-protein-coupled receptor, a membrane protein activated by extracellular ATP and UTP that drives calcium mobilization, chloride and bicarbonate secretion, and inflammatory signaling in epithelial, endothelial, and innate immune cell populations.

Supplied as a 100 µl liquid aliquot at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol cryoprotectant, the unconjugated rabbit antibody is validated for western blot analysis of receptor expression in cell lysates and for immunohistochemistry localization of P2RY2 in fixed tissue sections.

Researchers investigating airway surface liquid regulation, vascular smooth muscle remodeling, microglial responses in neuropathic pain models, or epithelial barrier dysfunction in cystic fibrosis and colitis use this reagent to confirm receptor upregulation after nucleotide stimulation. The vial supports flexible pairing with HRP, alkaline phosphatase, biotin, or fluorophore-conjugated secondary antibodies for chromogenic, chemiluminescent, or immunofluorescence detection, and aliquoting upon receipt preserves binding activity across multiple freeze-thaw cycles during long-term refrigerated storage.