Anti-P2RY11 Antibody - Identical to Abcam (ab180739)

This polyclonal reagent from Antibodies.com targets P2RY11, a G-protein coupled purinergic receptor that responds to extracellular nucleotides such as ATP and NAD+. The antibody was raised in rabbit against a synthetic peptide corresponding to a region of human P2RY11, and it is supplied as an unconjugated IgG preparation in a 100 µL vial. Validated applications include immunohistochemistry on human and rat tissue sections, where it is used to map receptor distribution in immune cells and epithelial barriers. P2RY11 couples to both Gq and Gs signaling pathways and is widely studied in the context of neutrophil chemotaxis, dendritic cell maturation, and T-cell activation, making this reagent useful for investigations of innate and adaptive immune signaling, as well as purinergic regulation in inflammatory and barrier tissues. The unconjugated format allows researchers to pair the reagent with their preferred secondary antibody and detection chemistry, including chromogenic and fluorescence-based IHC workflows. Short-term storage at 4 °C is recommended; aliquot upon receipt to limit freeze-thaw cycles across repeated use. For research use only.