Anti-P2RY1 Antibody

The P2RY1 protein is a G-protein-coupled purinergic receptor activated by extracellular ADP, best known for driving ADP-induced platelet aggregation and shaping vascular responses to injury. This rabbit polyclonal reagent from Antibodies.com was raised against P2RY1 and is supplied as 100 µl of unconjugated antiserum suited to Western blot and immunohistochemistry workflows. Cross-reactivity with human, mouse, and rat samples lets investigators compare receptor expression across patient-derived tissue and rodent disease models, supporting studies of arterial thrombosis, ischemic stroke, and purinergic signalling in the central nervous system. The polyclonal format increases the chance of recognizing multiple epitopes on the target, which is helpful when working with formalin-fixed sections where antigen masking is common.

The unconjugated presentation lets each laboratory pair the antibody with its preferred HRP, biotin, or fluorescent reporter for a tailored detection chemistry, and the rabbit host species is broadly compatible with secondary reagents and multiplex panels. Storage at 4°C for short-term use and at -20°C for long-term retention is recommended to preserve activity across repeated freeze-thaw cycles, so small aliquots should be prepared for frequent use. Researchers focused on P2Y1 pharmacology, megakaryocyte biology, and neurodegenerative disease models will find this reagent a flexible tool for characterizing P2RY1 distribution at the protein level, for research use only.