Anti-P2RX3 Antibody

Generated from a rabbit host, this polyclonal IgG reagent targets the P2X purinoceptor 3 (P2RX3), an ATP-gated cation channel expressed on nociceptive sensory neurons. Provided by Antibodies.com in a 50 µL aliquot, the unconjugated antibody is validated for Western blot detection in rat samples. P2RX3 has been studied in research contexts relating to chronic pain signaling, bladder afferent hyperactivity, and sensory neuron sensitization, making antibodies against it useful tools for neuroscience and urology investigations. The reagent should be stored refrigerated and protected from light; small aliquots are recommended to limit freeze-thaw cycles of the active fraction. Researchers commonly apply the antibody to dorsal root ganglion lysates and to bladder urothelium preparations to investigate ion-channel expression patterns under disease and pharmacological intervention models.